Palmitoylethanolamide (PEA) for Non-Flea Hypersensitivity Dermatitis in Cats

This is an interesting little study that tested using PEA in 57 cats with NFHD (Non Flea Hypersensitivity Dermatitis). It is also called “Feline Atopy”. Your cat suffers it as allergic dermatitis – just like humans. The results showed that PEA delayed relapse significantly when the steroids were stopped.

There are 3 main categories of allergic skin disease in cats including Flea Allergy Dermatitis, Food Induced Hypersensitivity dermatitis and the subject of todays article Non-flea (non-food) Hypersensitivity Dermatitis. This last one is similar to atopic dermatitis in dogs. As you can see below it is a nasty condition.

Image Source: https://www.researchgate.net/publication/316820157_Cutaneous_Hypersensitivity_Dermatoses_in_the_Feline_Patient_A_Review_of_Allergic_Skin_Disease_in_Cats

In this study, cats were in two groups. The experimental group fed PEA once daily at a rate of 15mg/kg plus a 28 day tapering dose of methylprednisolone. The control group was given just the methylprednisolone. The test was how long it took for the relapse of the nasty rashes for the two groups.

Cats given PEA took longer to relapse in the initial part of the study. Which is great news for cats.

Pruritus (itchy skin) scores in the cats worsened after the withdrawal of the steroid as expected, but scores were significantly lower in the PEA group.

This study shows that PEA may offer a steroid-sparing effect, and there appeared to be some benefit in slowing the relapses. Not earth-shattering – but still a possible useful tool to help very miserable moggies.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852539/

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